منابع مشابه
Pazopanib induced hand-foot syndrome
A 55-year-old male was diagnosed as a case of metastatic renal cell carcinoma (clear cell histology) and started on tyrosine kinase inhibitor (TKI) pazopanib. He reported back to us 2 weeks later with painful, erythematous and desquamating lesions of the hands and soles. On examination, erythematous and desquamating lesion involving dorsum of hands and soles consistent with grade 2 hand-foot sy...
متن کاملManagement of Paclitaxel-induced hand-foot syndrome.
BACKGROUND Hand-foot syndrome (HFS), also known as acral erythema or palmoplantar dysesthesia, is a manifestation of painful erythema and dysesthesia mostly occurring in the palms and soles. Although many chemotherapeutic agents have been shown to cause HFS, it remains an uncommon adverse cutaneous manifestation of paclitaxel. CASE REPORT We report a case of paclitaxel-induced grade 3 HFS in ...
متن کاملPazopanib Induced Hand-Foot Syndrome in a Patient Previously Treated with Sunitinib: A Possible Cumulative Skin Toxicity?
Hand-foot syndrome (HFS), also known as palmar-plantar erythrodysesthesia, is a skin toxicity that could be observed during target therapies such as with tyrosine-kinase inhibitors (TKI). It usually develops within the first 2 4 weeks of drug administration. We present a case of HFS induced by Pazopanib after 2 months of treatment, in patients previously treated with Sunitinib, suggesting a pos...
متن کاملSunitinib Induced Immune Thrombocytopenia
Sunitinib is an oral tyrosine kinase inhibitor which prevents tumor growth and metastatic progression. It was approved for treatment of advanced renal cell cancer, gastrointestinal stromal tumor and advanced pancreatic neuroendocrine tumors. It has several adverse reactions on multi organ systems including hematologic system. Although the neutropenia and thrombocytopenia commonly happens as Gra...
متن کامل[Hand-foot syndrome (palmar-plantar erythrodysesthesia].
The hand-foot syndrome (HFS) is an erythematous skin lesion of the palma and planta of the hand and feet is most often caused by cytostatic chemotherapy. The impact on the patients' quality of life depends on the extent of the disease. The pathogenesis of the hand-foot syndrome has not yet been sufficiently clarified and it can only be treated symptomatically. We performed an extensive literatu...
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ژورنال
عنوان ژورنال: JMS SKIMS
سال: 2009
ISSN: 0972-110X,0972-110X
DOI: 10.33883/jms.v12i2.34